Departures from the Guide

These modules are useful for educators seeking to teach IACUC members and staff to identify and evaluate departures from the Guide for the Care and Use of Laboratory Animal, and understand an implement relevant reporting requirements.

Module A: Departures from the Guide

Target Audience: Experienced IACUC administrators and members

Goal: To have the audience develop a skill set to evaluate departures from the Guide in conjunction with animal welfare and sound scientific practices


  • Recognize the relevant resources
  • Identify perceived departures from the Guide
  • Differentiate between perceived and true departures
  • Evaluate potential impacts from the departure
  • Identify reporting requirements and process

Active Learning Methods: Concept Mapping, Response Systems, Think-Pair-Share


Elizabeth Dodemaide, BVSc, MA
Associate Director, Laboratory Animal Services
Rutgers University

JoAnn Henry, LATG, CPIA
Regulatory Compliance Coordinator
NYU Langone Medical Center

Alison D. Pohl, MS, RLATG, CPIA
Research Compliance Monitor/IACUC Administrator
UConn Health

Claudia Swanson, LATG
Associate Director, Office of Animal Research Support
Yale University

Sandra L. Wilkins, LVT, RLATG, CPIA
IACUC Research Liaison, Animal Care Program
Michigan State University

Module B: Departures from the Guide or "Witch" Departure are We Talking About?

Target Audience: Both new and seasoned IACUC administrators and members

Goals: The goals of this training are to help IACUC members and administrative staff categorize "departures" from the Guide and fulfill the committee’s relevant oversight responsibilities.


  • Define "departure" relative to the Guide.
  • Compare the terms "must" vs "should" vs "may."
  • Differentiate between departures and noncompliance.
  • Use published guidance on departures correctly.
  • Determine when departures need to be reported in the semi-annual report and/or tracked.

Active Learning Methods: Concept Mapping, Response Systems, Think-Pair-Share


R. Wayne Barbee, PhD
Professor, Emergency Medicine
Virginia Commonwealth University

Susan B. Harper, DVM, MS
United States Department of Agriculture, Agricultural Research Service

Eileen M. Morgan, BS
Director, Division of Assurances
National Institutes of Health Office of Laboratory Animal Welfare

Jennifer A. Perkins, MA, CPIA
Director, Office of Animal Research Oversight
University of California, Los Angeles

Noé Tirado-Muniz, DMV, DVM, MS, CPIA
Director of the Office of the Attending Veterinarian
University of Kentucky

This material is based upon work supported by the National Science Foundation under Grant Nunber 1546975. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation.